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B12 shot can help overcome these barriers by providing a direct and efficient method of supplementation

Sequencing, data processing, and analysis parameters The study's primary aim was to determine whether 5A-1MQ treatment in combination with a switch from WD to LD rendered the intestinal microbiome comparable to that of mice continuously maintained on LD, and distinct from that of DIO mice switched to LD but given saline injections or mice maintained continuously on WD

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Structural lesions leading to vitamin B12 deficiency include regional ileitis, ileal resections, malignancies, etc