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[Products in use] Extracellular LDH : Cytotoxicity LDH Assay Kit-WST (Product code: CK12) Phosphatidylserine: Annexin V Apoptosis Plate Assay KitProduct code: AD12 Cell viability : Cell Counting Kit-8 (Product code: CK04) Intracellular Fe 2+ : FerroOrange (Product cose: F374) *Normalized with Hoechst 33342 fluorescence intensity Lipid peroxidation : Lipid Peroxidation Probe -BDP 581/591 C11- (Product code: L267) [Experimental conditions] Cell type: HepG2 cell(210 4 cells/well) Drugs: Staurosporin(5 mol/l), Erastin(25 mol/l), Erastin+RSL3(both 25 mol/l) *Diluted in serum-free medium

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The first phase includes initial processing of toxins like smoke, alcohol, pesticides, drugs, etc

Nat Chem Biol 13:9198 Markovic M, Ben-Shabat S, Keinan S, Aponick A, Zimmermann EM, Dahan A (2019) Lipidic prodrug approach for improved oral drug delivery and therapy

Protein precipitation with organic solvents can reduce matrix interference, but still a significant background persists

Studi1-2 dimostrano, infatti, che un prodotto ottenuto da fonti naturali viene assimilato maggiormente dal nostro organismo rispetto a quelli creati in laboratorio (di sintesi)