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Nature 458 (7239), 762765

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Even so, in healthy adults, even with strict vegetarian patterns, a clinical deficiency is uncommon because endogenous synthesis usually meets needs, although context (age, nutritional status, illness) can modify this situation

Higher TMAO levels are linked to obesity and vitamin D deficiency, while causality is unknown

Supplementary vitamin C in the treatment of Parkinson's disease

When you should take it really depends on how you work out, how fast your body burns fuel and what you are trying to get out of it