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Even when absorbed, its hydrophobic nature often leads to efflux back into the intestinal lumen via the P-glycoprotein transporter, which is highly expressed in the intestine (Metzler et al., 2013)

Ceftriaxone ameliorates motor deficits and protects dopaminergic neurons in 6-hydroxydopamine-lesioned rats

doi: 10.1152/ajpgi.00173.2003, 40

L-carnitine may markedly lower blood pressure, have a positive effect on lipid profile and reduce the risk of heart attacks and death from cardiovascular incidents in people with cardiovascular disease

As for the metabolic features, therapy-refractory cancer cells in certain statuses could perform surprisingly sensitive to ferroptosis [58, 104, 105]

Under oxidative conditions, sulfide could react with oxidized thiol groups, particularly sulfenic acids