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After Hg 2+ was added (10 M) for 1.5 h, fluorescence in living cells was observed gradually (Figure 6b and Figure 6e), indicating that GSH-Rh6G2 and GNPs-GSH-Rh6G2 could enter the cells and that the release of RGCOOH was triggered by intracellular Hg 2+

Imaging cerebrovascular effects Coexistent cerebrovascular disease is increasingly recognised as having a synergistic effect on synucleopathies 156 and multiple studies have assessed imaging markers of cerebrovascular disease in relation to outcomes in PD