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3.8 Effect of heterologous expression of Am ABCC1 and Am ABCC2 on xenobiotic tolerance in transgenic yeast To investigate any cytoprotective effect of these transporters towards xenobiotics and herbicides, Am ABCC1 and Am ABCC2 were expressed in Saccharomyces cerevisiae ycf1 strain defective in the cadmium factor protein, an ABCC transporter

discovered that the mA demethylase ALKBH5 delays the progression of diabetic retinopathy by inhibiting ferroptosis via the mAYTHDF1ACSL4 axis, suggesting its potential as a therapeutic target [169]