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Indeed, also in the earlier reports on the effects of low- or high-frequency stimulation (10200 Hz), it was noted that either seizure occurrence was dampened or enhanced (e.g., [111])

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The cells were then centrifuged and suspended in 0.1 mL of citrate buffer

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Preclinical pharmacology of AZD5363, an inhibitor of AKT: pharmacodynamics, antitumor activity, and correlation of monotherapy activity with genetic background