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PubMed Central PMCID: PMC2657662

In the environment, humans and animals are exposed to numerous chemical forms of mercury, including elemental mercury vapor (Hg), inorganic mercurous [Hg (I)], mercuric [Hg (II)] and organic mercuric compounds

The hydrogen bond has been suggested to act as a gate, restricting entry of the solvent molecule into the active site and also regulating access of the substrate to the active site cleft that results in a rigid structural conformation around the binding pocket

(2024) 13:e2302752

Another avenue is advanced surface engineering to create coatings that are selectively permeable to contaminants but act as a robust physical and chemical barrier to biological macromolecules, thus preventing the non-specific interactions that initiate toxicity.186 Fig

Low GSH levels increase the risk of premature aging, cancer, heart disease, neurodegenerative disorders, and autoimmune conditions