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Nature 327:779, PMID: 3574469 Hitchler MJ, Domann FE (2007) An epigenetic perspective on the free radical theory of development

In addition, folate is synthesized and stored as poly-gamma-glutamate forms in plant cells and can be hydrolyzed into mono-glutamic forms by the enzyme gamma-glutamyl hydrolase (GGH), which has an important influence on the cellular homeostasis of folate [1, 24, 28]

10.1056/NEJMoa1910437 216

10.5414/cp203345 7 HuL.HuangQ.HuangS.FengZ

One analysis did report a reduced risk of melanoma, but this was a cancer-specific finding rather than evidence that high-dose B vitamins prevent cancer generally