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doi:10.4103/2249-4863.214985 Miao CY, Fang XJ, Chen Y, Zhang Q

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Because thiol compounds generally function as a reducing agent, ERG also plays a role such as Cys and glutathione

In addition to preserving mitochondrial morphology, PQQ attenuated the downregulation of PGC-1 and TFAM induced by angiotensin II (Ang II) or transaortic constriction (TAC)

But coming back to the skin, Ectoin protects both from PMs (Particulate Matters, including ultrafine) as well as PAHs (Polycyclic Aromatic Hydrocarbons) and heavy metals