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1074 Grazulis 2001b, p

Bozzetti F, Ravera E, Cozzaglio L, et al

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Extracts were clarified by centrifugation and filtration through a 0.45 m pore Spin-X filter (Corning), and the total protein concentration was determined by BCA assay

This small molecule compound was developed through sophisticated structure-guided design and binding calculations as part of a systematic effort to create membrane-permeable NNMT inhibitors with enhanced potency and selectivity