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Identifying these mutations may guide preventive measures and treatment

In addition to their use in cell encapsulation with 3D bioprinting, microfluidic technology/lab-on-a-chip systems can also be harnessed for cryopreservation, encompassing various aspects such as CPAs uptake and elimination, cell membrane characteristics, and the implications of temperature reduction and increase patterns [142, 143]

In contrast, the hypothetical strategy, outlined in the ICH guidelines [3] (also known as the trial product estimand in some clinical trials [29]), provides information on the pharmacological effect of the tested therapy under the assumption that intercurrent events will not occur

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