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In animal studies, in comparison to a control diet, HFD consumption resulted in increased hepatic IKK--SSG formation, leading to suppressed IKK- activation and subsequent NF-B suppression

Sulfonated nonsaccharide heparin mimetics are potent and noncompetitive inhibitors of human neutrophil elastase

Nut, corn, and popcorn consumption and the incidence of diverticular disease

while preclinical models consistently demonstrate robust tumor suppression, outcomes in human clinical trials have been more modest, largely attributed to rapid systemic elimination and insufficient tissue accumulation within the gastric mucosa

Table 1 Diverse sources and types of polyphenols, their antioxidant properties, and modes of action

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