glutathione transferases a structural perspective Functional and Diversity of Insect S-transferases in Xenobiotic Adaptation Glutathione-S-Transferases as Potential Targets for

doi: 10.1126/science.2479986

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Glycolysis may be summarized in this context as: Glucose + NAD + Pyruvate + NADH + 2ATP But to allow glycolysis to continue the NADH is reoxidized to NAD + : Pyruvate + NADH Lactate + NAD + So the sole product of glycolysis for the erythrocyte is ATP (primarily for active cation transport to maintain cell shape) lactate passes into the blood for recycling

Indeed, both heme and hemin activate erythroid differentiation in vitro and in vivo , manifested by increased hemoglobin production 5

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Redox Signal 34 (9), 750764