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Regulation of hepatic glucose uptake and storage in vivo

Xie J, Yan J, Ji K, et al

(42), and Papandreou et al

Neuschwander-Tetri BA, Loomba R, Sanyal AJ, Lavine JE, Van Natta ML, Abdelmalek MF, Chalasani N, Dasarathy S, Diehl AM, Hameed B, Kowdley KV, McCullough A, Terrault N, Clark JM, Tonascia J, Brunt EM, Kleiner DE, Doo E (2015) Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial

J Androl 21 : 347354 Carson CC (1981) Francois Gigot de la Peyronie (16781747)

In the context of hepatic IR associated with non-alcoholic fatty liver disease (NAFLD), this molecular pathway becomes dysregulated, leading to impaired suppression of hepatic gluconeogenesis