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Abbreviations ASCA anti- Saccharomyces cerevisiae antibody FGID functional gastrointestinal disorders GF germ-free IEB intestinal epithelial barrier IBD inflammatory bowel disease IBS irritable bowel syndrome IBS-C constipation-predominant irritable bowel syndrome IBS-D diarrhea-predominant irritable bowel syndrome IBS-M irritable bowel syndrome with mixed bowel habit LPS lipopolysaccharides SCFA short-chain fatty acids

L-Glutathione (GSH) is an antioxidant in plants, animals, fungi, and some bacteria and archaea

qPCR expression analysis showed that the key predictors from logistic regression and decision tree modeling were differentially expressed according to NAC response (Supplementary Fig

The glutathione pathway of clearance is directly assisted by IV glutathione

Palma, G

Thus, we concluded that GPX4, DHODH, and LDHB work in parallel to suppress mitochondrial lipid peroxidation and thus protect against mitochondria-associated ferroptosis