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they create what researchers refer to as a massive immunological "energy sink." Because the immune cells (particularly T-cells and memory lymphocytes) are trapped in a state of severe oxidative stress, they are forced to consume excessive amounts of the host's energy just to survive the ongoing cellular damage and attempt repairs

10.1016/j.intimp.2026.116254 22 HongL.ZhengL.HeY

J Neuroimmunol

Recent studies suggest that the tumor microenvironment plays a significant role in determining the type of fuel that tumors use to grow

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