glutathione binding drugs transferases as mediators of signaling pathways involved in cell proliferation and cell death Glutathione dynamics in subcellular compartments

They have been shown to inhibit IgE-mediated human mast cell and peripheral blood basophils mediator release in vitro [107]

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Co-immunoprecipitation studies demonstrated that the peptide reduces eNOS/caveolin-1 binding by approximately 50%, effectively doubling the available eNOS for nitric oxide production

Additionally, monotropein effectively inhibits cisplatin-induced OS by lowering MDA levels and boosting GSH, SOD, and CAT enzymatic functions

doi: 10.1016/j.ijbiomac.2023.127708

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