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The detoxification against H 2 O 2 in mitochondria occurs mainly through the GSH redox system, including the glutathione peroxidases (Gpxs) and GSH reductases, as well as the presence of peroxiredoxins (Prxs

However, its underlying mechanisms is intricate, and research methodologies face limitations

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Reaction mixtures were incubated at 37 C for a desired amount of time (for H 2 S detection in the Jerome J605, 1 h with supraphysiological reaction mixture and 6 h with physiological reaction mixture

The SOD (IU) was determined with the inhibition rate of the oxidation of adrenaline to adrenochrome as the source of peroxide radicals, which is proportional to the activity of SOD and absorbs at a maximum wavelength of 480 nm [29]

Finally, other compounds such as lipids and aromatic compounds play important roles in their pharmacological activities such as antioxidant and immunosuppressive effects