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Amongst the genes having the capacity to save the methionine auxotrophy of CYS4 -OE cells, six genes had a strong effect: MUP1 (a methionine permease), MMP1 (a S-methylmethionine permease), STP2 (a transcription factor that activates the transcription of amino acid permease genes), MCK1 (one of the four genes that encode glycogen synthase kinase 3 (GSK3) homologs in yeast), and UBP7 and UBP11 , two ubiquitin specific proteases involved in endocytosis and in the sorting of internalized receptors (Tardiff et al., 2013

Maternal low-protein diet induces changes in the cardiovascular autonomic modulation in male rat offspring

[Abstract] Biochem Biophys Res Commun

All of that is without regard for the potential adverse effects that even base- or prime-editing will leave in treated glial or vascular cells over time in an intrablood/intracranial process

Skin biopsy as a tool to assess distal small fiber innervation in diabetic neuropathy