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This of itself might lead one to suppose that they have a broadly similar, ultimate type of cause (i.e., something labelled Y in Figure 1), and the evidence for this something points rather squarely at an infectious origin (see Table 3)

TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

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MAPK14/p38-dependent modulation of glucose metabolism affects ROS levels and autophagy during starvation

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(2006) Metabolomic database annotations via query of elemental compositions: Mass accuracy is insufficient even at less than 1 ppm