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Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo

AOD-9604 was subsequently placed in Category 2 of the bulk drug substance nomination list, then later withdrawn from that nomination in April 2026

Feldman, S

This is clear from both the limited reductions in prevalence achieved over the past decade, and also from the health economic modelling predictions we summarise here

doi: 10.1016/j.fsi.2018.03.020 345 XiaJ.LuL.JinC.WangS.ZhouJ.NiY.et al

While affecting both genders, it frequently manifests initially in women and individuals with a genetic predisposition (4)