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Ferroptosis, a recently discovered form of regulated cell death (RCD), is characterized by iron dependence, lipid peroxidation, increased reactive oxygen species (ROS), and disruption of mitochondrial metabolism [14, 15]

Yan X, Payet LD, Baxter RC, Firth SM

Inside the cell metformin inhibits mitochondrial respiratory-chain complex 1, resulting in reduced ATP levels and increased AMP

Methods Ethics All patients with neuroblastoma were enrolled in the German Neuroblastoma Trial (NB97, NB2004, NB 2016) and approved by the ethics committee of the University of Cologne

Dwivedi S, Mukherjee D, Lohia N, Thakur N, Hans R, Mohan R , Sud R, Darling HS

Understanding what real users experience, what the data actually supports, and where the genuine risks hide requires cutting through layers of hype and fear alike