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Without a systematic framework, researchers risk wasting time, money, and emotional energy on poorly designed protocols that produce ambiguous results

It has shown promising effects in animal models by promoting tissue regeneration and reducing inflammation

The search spanned from the earliest publication on this topic in 2014 to relevant papers published as recently as March 2024

Davis, M

A Cochrane Review of three randomized trials found that high oral doses of 1,000 to 2,000 mcg normalized serum B12 about as well as intramuscular injections