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Description

2020;192(46):E145368

Regulation of lipopolysaccharide-induced inflammatory response by glutathione S-transferase P1 in RAW264.7 cells

About NAD+ (Nicotinamide Adenine Dinucleotide) is a powerful coenzyme found in every cell of the body, responsible for supporting cellular energy, DNA repair, and overall vitality

Before glutaminase 2 (GLS2) transforms glutamine into glutamate (Glu) in the mitochondria, SLC1A5 is a subunit of importers SLC1A5/SLC38A1, which move glutamine into the cytoplasm of cells [66]

Under conditions of limited iron availability, Ferritin can be targeted by specific nuclear receptor coactivator 4(NCOA4) [22], which facilitate its degradation by lysosomal enzymes and the stored iron is released