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BBB damage following most mild TBI in which seizures or epilepsy develop is persistent, and perivascular and distributed IgG staining results have been found in the grey matter of TBI patients who died 147 years after initial injury (111, 112)

PMID: 42167448 Biochem Pharmacol Mutant NPM1-regulated estrogen signaling promotes leukemia cell survival by upregulating HGF and represents a therapeutic vulnerability

BMC Genomics 20(1):877

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This influences OXPHOS function and leads to increased ROS production (31)