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Considering that oxidative stress plays a crucial role in the pathogenesis of SSc, GGT may be a marker associated with the development of SSc. To examine the link between gamma-glutamyl transferase levels and the risk for SSc, Kwon and colleagues conducted a nationwide, retrospective cohort study of more than 6 million adults without SSc from the Korean National Health Insurance Service database

Cui H, Huang J, Lu M, Zhang Q, Qin W, Zhao Y, et al

10.1111/j.1439-0531.2004.00522.x

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Advanced experimental systems, such as ovarian organoids, may further improve mechanistic studies