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De novo pyrimidine synthesis initiates with carbamoyl phosphate formation, and de novo purine synthesis begins with the binding of phosphoribosyl pyrophosphate (PRPP) to glutamine

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[DOI] [PubMed] [Google Scholar] 164.Petrine J.C.P., Del Bianco-Borges B

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We believe the RUC's use of the new PE worksheet in developing and submitting recommendations helps us simplify and standardize the hundreds of clinical labor tasks currently listed in our direct PE database