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Authors: We found that oral vitamin B 12 replacement at 1000 g daily was adequate to replace vitamin B 12 levels in patients with pernicious anemia

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the invention encompasses use of one or more cations of the invention to treat obesity or related chronic metabolic condition, including metabolic syndrome, pre-diabetes, type-2 diabetes, obesity-linked diseases (e.g., non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, CVDs, and the like)