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Efficacy and safety of probiotics in irritable bowel syndrome: A systematic review and meta-analysis

This historical context underscores its foundational connection to gut health and repair mechanisms

Conclusion CLE remains a clinically heterogeneous and therapeutically challenging disease, complicated by variable phenotypes, limited approved treatments, and a lack of skin-specific outcome measures

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It also stimulates the activation of a unique population of T cells called T follicular helper (TFH) cells, which promote B cell differentiation into antibody-secreting plasma cells (9)

Since there is no cure and vaccination is not yet approved, the key to controlling this disease is prevention