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Kat6a +/ mice were crossed to WT C57BL/6 mice to obtain E16.5 Kat6a +/+ and Kat6a +/ foetuses and adult mice

The cross-sectional analysis presented in this work is based on clinical and biomarker data obtained at baseline

[5] Shimizu, M., Cashman, J

378,379 Furthermore, recent studies have shown that TGF- influences lipid metabolism

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Specialized pro-resolving lipid mediators (SPMs), the oxygenated derivatives of these fatty acids, exhibit anti-inflammatory properties by dampening pro-inflammatory factor expression, bolstering anti-inflammatory factor production, and facilitating the shift from pro-inflammatory M1 macrophages to anti-inflammatory M2 macrophages