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[DOI] [PubMed] [Google Scholar] 168.Sikand M, Sharma P

PMID: 29176395

Longer incubation times can make it challenging to identify the early metabolic impairments directly caused by the exposure to the drug

The farnesoid X Receptor (FXR) pathway and takeda G protein-coupled receptor 5 (TGR5), which are directly activated by BAs, are highly expressed in the kidney after activation and can play a role in slowing down renal injury (9094)