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Ohla et al., 2019)

Additionally, these reactive species induce DNA oxidation, leading to mitochondrial and nuclear DNA mutations, further impairing ATP production and exacerbating ETC dysfunction

Antipyretic effects are thought to be due to the central (CNS) inhibition of COX-1 and COX-2 variant enzymes

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However, gait compensatory effects are known to cause an increased variance, which is a commonly observed phenomenon when measuring gait in rodents 44