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Description

The group that received gemcitabine, cisplatin, and bevacizumab had the highest overall survival (OS) compared to the other groups, suggesting a potential benefit of this combination therapy [165]

The potential effects described in this section are based on limited animal and cell studies

The preferential effect of Clemastine on F3/Contactin-1/Notch-1 compared to Jagged-1/Notch-1 justifies its remyelinating effect in an experimental model of multiple sclerosis in rats