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Regarding oxidative stress, the enzymatic systems that contribute the most to the generation of ROS include the proteins that are bound to the plasma membrane, such as the family of NADPH oxidases [17,18], the enzymatic systems that participate in the lipid metabolism within peroxisomes and the activity of various cytosolic enzymes such as cyclooxygenases

In cancer, MDH1 deregulation has been linked to autophagy-associated energy transfer and tumor proliferation (83)

The in vitro chondrogenic potential was the highest in pellets generated by MSCs with high GSH levels, with increased ECM formation and chondrogenic marker expression

Growth Des, 2012, 12, 876882

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Environ Sci Pollut Res Int (2017) 24:1495508