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This feature and its negative charge at physiological pH imply the existence of specific carriers to import GSH from the cytosol to the mitochondrial matrix, where it plays a key role in defense against respiration-induced reactive oxygen species and in the detoxification of lipid hydroperoxides and electrophiles

Angelman Syndrome mice showed similar improvements in hippocampal plasticity in addition to improved function in a fear-conditioning task, indicating that this increased hippocampal function correlates with improved memory

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