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ROS-induced DNA mutations, strand breaks, and chromosomal abnormalities through their interaction with nitrogenous bases and the sugarphosphate backbone are fundamental contributors to the onset of cancer

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short-chain fatty acids (SCFAs) produced by dietary fiber fermentation, particularly butyrate, enhance intestinal tight junction protein expression, reduce intestinal permeability, and decrease endotoxin translocation into the bloodstream

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The per-weight dose they gave the mice was consistent with what people typically consume in supplements