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(1) This compound has emerged as a significant research tool for investigating the role of NNMT in metabolic regulation, energy expenditure, and cellular energetics

2 PMC (2024)NNMT inhibition mitigates obesity-related metabolic dysfunctions in animal models

Blocking NNMT restores intracellular NAD+, which fuels mitochondrial energy production and cellular repair throughout your body

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

Additionally, the microbiomes in these treatment groups were compared to both age-matched lean and obese controls