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MMPs mediate the degradation of collagen and other extracellular matrix components within the fibrous cap, thereby disturbing the dynamic balance of collagen synthesis and degradation that underlies plaque stability.When collagen degradation becomes relatively enhanced and compensatory synthesisprimarily mediated by vascular smooth muscle cellsis insufficient, the structural integrity of the fibrous cap may be compromised

These findings position AC as a promising therapeutic agent for treating a range of pulmonary disorders, warranting further clinical investigation

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