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This years Deltopia, Lt

Then, the ubiquitinated target protein is sent to the proteasome, a protein complex that will degrade the target protein into small peptides (Micel et al, 2013)

DEMETER2 (for RNAi) and CERES (for CRISPR) scores express how lethal is a knockdown or knockout, with highly negative values indicating stronger dependency of that gene

Taken together, these observations support a hypothetical model in which MexPQOpmE contributes to copper homeostasis by exporting [fluopsin] 2 Cu(I) complexes rather than free copper ions