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Expression of mt-roGFP in park 13 tyrosine hydroxylase positive neurons showed significantly reduced mitochondrial ROS accumulation under Sp treatment as compared to untreated ones, highlighting potential mitochondrial recovery and prevention of oxidation induced cell death in dopamine producing neurons (Fig

Itaconate increases Nrf2 expression and reduces lipopolysaccharide-induced ferroptosis in macrophages

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Afterward, Yap1 promotes the activation of genes (Montibus et al., 2015

When vitamin E reacts with a free radical, it becomes a radical itself, and if there is not enough ascorbic acid for its regeneration, it will remain in this highly reactive state and support the autoxidation of linoleic acid [53]

1,2-dipalmitoyl- sn -glycero-3-phosphocholine (DPPC), 1,2-distearoyl- sn -glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] (DSPE-PEG-maleimide), 2,7-dichlorofluorescein diacetate (DCFH-DA), and 1,2-dioleoyl- sn -glycero-3-phosphoethanolamine-N-(cyanine 5.5) (DOPE-Cy5.5) were purchased from Avanti Polar Lipids (Alabaster, AL, USA)