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By contrast, the detailed mechanistic investigations reported here point toward an anionic mechanism that depends on the ionization state of SetCys in its ring-opened and reduced form

Pathophysiology of the metabolic syndrome: implications for the cardiometabolic risks associated with type 2 diabetes

The constitutive 26S proteasome is expressed in nearly all tissues and cell types and is composed of a 19S regulatory particle harboring ubiquitin receptors and an ATPase ring for protein unfolding and a 20S proteolytic core particle