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In the data acquisition unit, the signals from the detectors, together with the synchronization signal, are acquired with a time-correlated single-photon counting (TCSPC) module (Time Tagger Ultra, Swabian Instruments GmbH, Germany)

Tillmann T., Kamino K., Dasenbrock C., Ernst H., Kohler M., Morawietz G., Campo E., Cardesa A., Tomatis L., Mohr U

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In DKD, continuous activation of RAAS leads to elevated pressure within the glomeruli, enhances the production of ROS, promotes tissue damage, triggers the release of proinflammatory cytokines, and stimulates the development of fibrosis in the glomeruli and tubulointerstitium