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Low basal level of NRF2 is therefore re-established by KEAP1-mediated ubiquitination and degradation, and the NRF2 signalling pathway is turned off [166,167,168] (Fig

Neural progenitor cells used in this study were derived from the WA09 human ESC line (H9 ESC) derived by Dr James Thomson and distributed by WiCell Research Institute under SLA agreement

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Drug Metab Rev 36 , 279299, doi: 10.1081/DMR-120034001 (2004)

Synthesis of 4-aminoquinoline analogues and their platinum(II) complexes as new antileishmanial and antitubercular agents