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However, the structural polymorphism of A, including monomers, soluble oligomers, protofibrils, and amyloid plaques, along with numerous pathogenic variants, complicates the selection of precise targets and adds to the complexity of designing effective drugs

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P., Keck, T., Auer, G., and Habermann, J

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Synthetic pathway for Melatonin Lack of vitamin B12 pushes the pathway to both degradation of serotonin, but also to the metabolic destruction of high levels of intracellular tryptophan with increased in KA and QA