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This is consistent with GHK-Cus known role in upregulating collagen synthesis in dermal fibroblasts, a mechanism confirmed in a comprehensive review in Biomolecules documenting GHK-Cus influence across more than 4,000 human genes involved in tissue remodeling and repair

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However, critics of the ban pointed out that many of these peptides have been used for years with a strong safety record in clinical practice and are approved in other countries