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70 Ferroptosis is closely related to several pathologic processes, including inflammation, T-cell immunity, acute renal failure, blood disorders, ischemia/reperfusion injury, and CNS diseases

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In mammals, sulforaphane can similarly upregulate stress-induced signaling pathways, including the Nuclear Factor Erythroid 2-related Factor 2 (NRF2) transcriptional pathway, which is conserved across mammalian species, but absent from plants (Gacesa et al., 2016

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