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It resets gene expression to a "younger/healthier" state suppressing inflammatory and metastatic genes while activating repair and remodeling genes

In contrast, many underutilized species, often referred to as orphan crops, receive limited research attention and funding despite their capacity to enhance nutrition, genetic diversity, and food security (Mukuwapasi et al., 2024) The FAO identifies amaranth as one such orphan crop highlighting its significant potential but also the absence of standardized agronomic protocols, phenotyping frameworks, genetic and molecular research, and improved varieties suitable for widespread cultivation (FAO, 2010)

Nestle Nutrition Institute workshop series

10.1038/s41419-019-2143-7 31 GaoW.HuangZ.DuanJ.NiceE

Thus, the induction of sulfate uptake is not completely derived from upregulation of the transcript but another, unknown, post-transcriptional mechanism is necessary for proper regulation

Inhibition of tumour promotion in mouse skin by extracts of rooibos (Aspalathus linearis) and honeybush (Cyclopia intermedia), unique South African herbal teas