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A common polymorphism in HIBCH influences methylmalonic acid concentrations in blood independently of cobalamin

10.1681/ASN.2010030246 J

But as with any injection, a few mild effects are possible: Temporary redness or swelling at the injection site Mild nausea or digestive shifts Headache or light dizziness A brief boost in energy or restlessness (common if you're sensitive to B12) Bright yellow or orange urinetotally normal, just your body clearing excess B12 If anything feels off or persists, check in with your provider

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This dizziness is usually mild and transient but can be concerning if it affects daily activities or increases fall risk