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Nat Med 23(11):13621368 Saha SK, Islam SMR, Abdullah-Al-Wadud M, Islam S, Ali F, Park KS (2019) Multiomics analysis reveals that GLS and GLS2 differentially modulate the clinical outcomes of cancer

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Paradoxically, endogenous SAM accumulation or exogenous SAM treatment inhibits CRC proliferation, induces apoptosis (178, 179), and reverses promoter hypomethylation of oncogenes such as c-Myc and Ras (180)

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Zhang J, Fan Y, Liang H et al (2024) Global, regional and national temporal trends in Parkinsons disease incidence, disability-adjusted life year rates in middle-aged and older adults: a cross-national inequality analysis and Bayesian age-period-cohort analysis based on the global burden of disease 2021